Which area is primarily responsible for language comprehension in the brain?

Wernicke's area is primarily responsible for language comprehension in the brain. Located in the superior temporal gyrus of the dominant hemisphere (usually the left hemisphere for right-handed individuals), this area plays a crucial role in understanding spoken and written language. People with damage to Wernicke's area may exhibit fluent but nonsensical speech, indicating that while they can produce words, they struggle with comprehension, thereby underscoring the significance of this area in processing and making sense of language.

Broca's area, found in the frontal lobe, is more associated with language production and speech articulation rather than comprehension. While the angular gyrus and Heschl's gyrus are involved in related linguistic processes—such as reading, writing, and the auditory processing of language—the primary function of language comprehension resides in Wernicke's area, making it the correct answer.