Delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage (SAH) is a result of what?

Delayed cerebral ischemia following an aneurysmal subarachnoid hemorrhage (SAH) primarily results from vasospasm. This phenomenon is characterized by the narrowing of blood vessels, which can occur days after the initial hemorrhagic event. After the rupture of an aneurysm, blood enters the subarachnoid space, leading to the release of inflammatory mediators that can induce smooth muscle contraction and result in vasospasm of the surrounding cerebral arteries.

This constriction diminishes blood flow to the brain tissue, which can lead to ischemia and neurological deficits. It is crucial to monitor and manage this condition, as timely treatment of vasospasm can prevent further complications and improve outcomes for the patient. Understanding this mechanism highlights the importance of vigilant follow-up and potential therapeutic interventions aimed at preventing or reversing vasospasm after SAH.